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Home Antibody All anti-NLRP12 antibodies

Anti-NLRP12 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320073 Rabbit Polyclonal NALP12 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenNALP12 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP12.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferNALP12 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NALP12 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NLR family, pyrin domain containing 12 (NLRP12), transcript variant 1
Alternative NameCLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
Database LinkNP_150639
Entrez Gene 91662 Human
Entrez Gene 378425 Mouse
Entrez Gene 292541 Rat
FunctionNALP12 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-κB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of NALP12 in human brain tissue with NALP12 antibody at 5 ug/mL.

IF Image
Immunofluorescence of NALP12 in human brain tissue with NALP12 antibody at 20 ug/mL.


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