Home Antibody All anti-NLRP12 antibodies
Anti-NLRP12 Antibody Polyclonal
Also for NLRP12 (NM_033297)
|NALP12 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP12.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|NALP12 Antibody is supplied in PBS containing 0.02% sodium azide.|
|NALP12 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens NLR family, pyrin domain containing 12 (NLRP12), transcript variant 1|
|CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2|
Entrez Gene 91662 Human
Entrez Gene 378425 Mouse
Entrez Gene 292541 Rat
|NALP12 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-κB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.|
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Western blot analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 ug/mL.
Immunohistochemistry of NALP12 in human brain tissue with NALP12 antibody at 5 ug/mL.
Immunofluorescence of NALP12 in human brain tissue with NALP12 antibody at 20 ug/mL.