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Home Antibody All anti-NLRP12 antibodies

Anti-NLRP12 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320073
  • Rabbit Polyclonal NALP12 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for NLRP12 (NM_033297)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenNALP12 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP12.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferNALP12 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NALP12 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NLR family, pyrin domain containing 12 (NLRP12), transcript variant 1
Alternative NameCLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
Database LinkNP_150639
FunctionNALP12 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-κB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
Related Pathway

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WB Image
Western blot analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 ug/mL.
IHC Image
Immunohistochemistry of NALP12 in human brain tissue with NALP12 antibody at 5 ug/mL.
IF Image
Immunofluorescence of NALP12 in human brain tissue with NALP12 antibody at 20 ug/mL.

 

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