OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-IL33 antibodies

Anti-IL33 Antibody 12H6D12

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320070
  • Mouse IL-33 Monoclonal Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC409498) , 20ug
100ug $325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)

OriGene Data

ImmunogenMouse monoclonal IL-33 antibody was raised against the recombinant IL-33 protein.
Clone Name12H6D12 IsotypeIgG1
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 ug/ml, IHC: 5 ug/ml
BufferIL-33 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IL-33 Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Reference Data

Target NameHomo sapiens interleukin 33 (IL33), transcript variant 2
Alternative NameC9orf26; DVS27; IL1F11; NF-HEV; NFEHEV
Database LinkNP_001186569
FunctionIL-33 Monoclonal Antibody: Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1αβ, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-κB and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. Despite its predicted molecular weight, IL-33 will often run at higher molecular weight in SDS-PAGE.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IL-33 using 125ng of recombinant IL-33 with IL-33 antibody at 1 ug/mL.
IHC Image
Immunohistochemistry of IL-33 in human lymph node tissue with IL-33 antibody at 5 ug/mL.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title