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Home Antibody All anti-LZTS2 antibodies

Anti-LZTS2 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320051 Rabbit Polyclonal LZTS2 Antibody 100ug $325 3-7 Days
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Also for LZTS2 (NM_032429)
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OriGene Data

ImmunogenLZTS2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LZTS2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *IHC Suggested DilutionsIHC: 5 ug/mL
BufferLZTS2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LZTS2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nameleucine zipper, putative tumor suppressor 2
Alternative NameLAPSER1
Database LinkNP_115805
Entrez Gene 84445 Human
FunctionLZTS2 Antibody: The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway. It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.
Related PathwayDruggable Genome

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IHC Image
Immunohistochemistry of LZTS2 in human placenta tissue with LZTS2 antibody at 5 ug/mL.


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