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Home Antibody All anti-KREMEN1 antibodies

Anti-KREMEN1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320040 Rabbit Polyclonal KREMEN1 Antibody 100ug $325 In Stock
LC422073 KREMEN1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for KREMEN1 (NM_001039570)
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OriGene Data

ImmunogenRabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.125 - 0.25 ug/mL
Predicted MW Explanation 54 kDa
BufferKREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KREMEN1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens kringle containing transmembrane protein 1 (KREMEN1), transcript variant 3
Alternative NameKREMEN; KRM1
Database LinkNP_001034659
Entrez Gene 83999 Human
Entrez Gene 84035 Mouse
Entrez Gene 114107 Rat
FunctionKREMEN1 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KREMEN1 in rat small intestine tissue lysate with KREMEN1 antibody at (A) 0.125 and (B) 0.25 ug/mL

IHC Image
Immunohistochemistry of KREMEN1 in human small intestine tissue with KREMEN1 antibody at 5 ug/mL.

IF Image
Immunofluorescence of KREMEN1 in human small intestine tissue with KREMEN1 antibody at 20 ug/mL.


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