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Anti-WIZ Antibody Polyclonal
|WIZ antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TFF3.|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|WIZ Antibody is supplied in PBS containing 0.02% sodium azide.|
|WIZ Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens widely interspaced zinc finger motifs (WIZ)|
|WIZ Antibody: WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.|
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Western blot analysis of WIZ in rat lung tissue lysate with WIZ antibody at 1 ug/mL.
Immunohistochemistry of WIZ in human brain tissue with WIZ antibody at 2.5 ug/mL.