Home Antibody All anti-HHATL antibodies
Anti-HHATL Antibody Polyclonal
Also for HHATL (NM_020707)
|HHATL antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human HHATL.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 2.5 ug/ml
|HHATL Antibody is supplied in PBS containing 0.02% sodium azide.|
|HHATL Antibody is affinity chromatography purified via peptide column.
|Homo sapiens hedgehog acyltransferase-like (HHATL), transcript variant 1|
|C3orf3; GUP1; MBOAT3; MSTP002; OACT3|
Entrez Gene 57467 Human
Entrez Gene 74770 Mouse
Entrez Gene 301073 Rat
|HHATL Antibody: The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.|
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Western blot analysis of HHATL in 3T3 cell lysate with HHATL antibody at 1 ug/mL.
Immunohistochemistry of HHATL in human skin tissue with HHATL antibody at 2.5 ug/mL.
Immunofluorescence of HHATL in human skin tissue with HHATL antibody at 20 ug/mL.