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Home Antibody All anti-DDX60 antibodies

Anti-DDX60 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319959 Rabbit Polyclonal DDX60 Antibody 100ug $325 3-7 Days
LC413632 DDX60 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenDDX60 antibody was raised against a 17 amino acid synthetic peptide near the center of human DDX60.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, IF: 20 ug/mL
Predicted MW Explanation 188 kDa
BufferDDX60 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DDX60 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 (DDX60)
Alternative NameFLJ10787; FLJ20035
Database LinkNP_060101
Entrez Gene 55601 Human
Entrez Gene 234311 Mouse
Entrez Gene 100360801 Rat
FunctionDDX60 Antibody: DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DDX60 in A20 cell lysate with DDX60 antibody at (A) 1 and (B) 2 ug/mL.

IF Image
Immunofluorescence of DDX60 in A20 cells with DDX60 antibody at 20 ug/mL.


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