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Home Antibody All anti-FOXP3 antibodies

Anti-FOXP3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319911
  • Rabbit Polyclonal FOXP3 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402270) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for FOXP3 (NM_001114377)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml
BufferFOXP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification FOXP3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens forkhead box P3 (FOXP3), transcript variant 2
Alternative NameAIID; DIETER; IPEX; JM2; PIDX; XPID
Database LinkNP_001107849
FunctionFOXP3 Antibody: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FOXP3 in A549 cell lysate with FOXP3 antibody at (A) 1 and (B) 2 ug/mL.

 

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