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Anti-FOXP3 Antibody Polyclonal
Also for FOXP3 (NM_001114377)
|Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|FOXP3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|FOXP3 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens forkhead box P3 (FOXP3), transcript variant 2|
|AIID; DIETER; IPEX; JM2; PIDX; XPID|
|FOXP3 Antibody: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. |
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Western blot analysis of FOXP3 in A549 cell lysate with FOXP3 antibody at (A) 1 and (B) 2 ug/mL.