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Anti-TLX3 Antibody Polyclonal
Also for TLX3 (NM_021025)
|TLX3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX3.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 1 ug/ml
|TLX3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TLX3 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens T-cell leukemia homeobox 3 (TLX3)|
|TLX3 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL).|
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Western blot analysis of TLX3 in human spleen tissue lysate with TLX3 antibody at (A) 0.5 and (B) 1 ug/mL.