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Home Antibody All anti-TCTN3 antibodies

Anti-TCTN3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319883
  • Rabbit Polyclonal TCTN3 Antibody
100ug $325 3-7 Days
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WB(1)
IF(2)

OriGene Data

ImmunogenTCTN3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TCTN3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 4 ug/ml, IF: 20 ug/ml
BufferTCTN3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TCTN3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tectonic family member 3 (TCTN3), transcript variant 1
Alternative NameC10orf61; JBTS18; OFD4; TECT3
Database LinkNP_056446
FunctionTCTN3 Antibody: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Related Pathway

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WB Image
Western blot analysis of TCTN3 in HeLa cell lysate with TCTN3 antibody at (A) 1 and (B) 2ug/mL.
IF Image
Immunocytochemistry of TCTN3 in HeLa cells with TCTN3 antibody at 4 ug/mL.
IF Image
Immunofluorescence of TCTN3 in HeLa cells with TCTN3 antibody at 20 ug/mL.

 

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