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Anti-IL17RA Antibody Polyclonal
Also for IL17RA (NM_014339)
|IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA. |
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|IL-17RA Antibody is supplied in PBS containing 0.02% sodium azide.|
|IL-17RA Antibody is affinity chromatography purified via peptide column.
|Homo sapiens interleukin 17 receptor A (IL17RA), transcript variant 1|
|CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R|
|IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).|
Cytokine-cytokine receptor interaction
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Western blot analysis of IL17RA in A20 cell lysate with IL17RA antibody at 1 ug/mL.