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Home Antibody All anti-IL17RA antibodies

Anti-IL17RA Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319870 Rabbit Polyclonal IL-17RA Antibody 100ug $325 3-7 Days
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Also for IL17RA (NM_014339)
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OriGene Data

ImmunogenIL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation Predicted: 95 kDa Observed: 135 kDa
BufferIL-17RA Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IL-17RA Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens interleukin 17 receptor A (IL17RA), transcript variant 1
Alternative NameCANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R
Database LinkNP_055154
Entrez Gene 23765 Human
Entrez Gene 16172 Mouse
Entrez Gene 312679 Rat
FunctionIL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IL17RA in A20 cell lysate with IL17RA antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of IL-17RA in human spleen tissue with IL-17RA antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of IL-17RA in human spleen tissue with IL-17RA antibody at 20 ug/mL.


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