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Home Antibody All anti-LPIN1 antibodies

Anti-LPIN1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319846 Rabbit Polyclonal LPIN1 Antibody 100ug $325 3-7 Days
LC407897 LPIN1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenLPIN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LPIN1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation Predicted: 107 kDa Observed: 125 kDa
BufferLPIN Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LPIN1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens lipin 1 (LPIN1), transcript variant 2
Alternative NamePAP1
Database LinkNP_001248356
Entrez Gene 23175 Human
Entrez Gene 14245 Mouse
Entrez Gene 313977 Rat
FunctionLPIN1 Antibody: LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol (reviewed in 1). LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism (1,2). Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria (3,4) and it is also a candidate for several human lipodystrophy syndromes (5).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LPIN1 in K562 cell lysate with LPIN1 antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of LPIN1 in human small intestine tissue with LPIN1 antibody at 5 ug/mL.

IF Image
Immunofluorescence of LPIN1 in human small intestine tissue with LPIN1 antibody at 20 ug/mL.


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