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Home Antibody All anti-RAPGEF4 antibodies

Anti-RAPGEF4 Antibody Polyclonal

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SKU Description Amount Price Availability*  
TA319831 Rabbit Polyclonal EPAC2 Antibody 100ug $325 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for RAPGEF4 (NM_007023)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenEPAC2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human EPAC2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferEPAC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification EPAC2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), transcript variant 1
Alternative Name2; CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496
Database LinkNP_008954
Entrez Gene 11069 Human
Entrez Gene 56508 Mouse
Entrez Gene 252857 Rat
FunctionEPAC2 Antibody: EPAC2, also known as Rap guanine nuclear exchange factor 4 and cAMPGEF-II, is belongs to a family of cyclic adenosine monophosphate (cAMP) binding proteins with guanine nucleotide exchange factor. Like the related protein EPAC1, EPAC2 signaling plays a role in numerous cellular processes such as integrin-mediated cell adhesion, muscle contraction, learning and memory, cell proliferation, and inflammation. Recent evidence suggests that EPAC2 induces synapse remodeling and depression, with mutations in its gene being found in patients with autism.
Related Pathway Leukocyte transendothelial migration

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of EPAC2 in rat liver tissue lysate with EPAC2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of EPAC3 in mouse liver tissue with EPAC3 antibody at 2.5 ug/mL.
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Immunofluorescence of EPAC2 in mouse liver tissue with EPAC2 antibody at 20 ug/mL.
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