OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-RAPGEF3 antibodies

Anti-RAPGEF3 Antibody Polyclonal

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319816 Rabbit Polyclonal EPAC1 Antibody 100ug $325 3-7 Days
LC401841 RAPGEF3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
Add to Shopping Cart
spacer
WB(1)
IHC(1)
IF(1)
spacer
Also for RAPGEF3 (NM_001098531)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody

OriGene Data

ImmunogenEPAC1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human EPAC1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferEPAC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification EPAC1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens Rap guanine nucleotide exchange factor (GEF) 3 (RAPGEF3), transcript variant 1
Alternative Namebcm910; CAMP-GEFI; EPAC; EPAC1; HSU79275
Database LinkNP_001092001
Entrez Gene 10411 Human
Entrez Gene 223864 Mouse
Entrez Gene 59326 Rat
FunctionEPAC1 Antibody: EPAC1, also known as Rap guanine nuclear exchange factor 3 and cAMPGEF-I, is widely expressed but most prominently in brain, heart, kidney, pancreas, spleen, ovary, thyroid and spinal cord. EPAC1 is a cAMP-binding protein with intrinsic guanine nuclear exchange factor activity that couples cAMP production to the activation of Rap, a GTPase belonging to the Ras family. This activation of Rap influences numerous cellular processes such as integrin-mediated cell adhesion, vascular endothelial barrier formation, and cardiac myocyte gap junction formation. Recently, EPAC1 has been suggested to also be involved in the cAMP-dependent regulation of ion channel formation, intracellular Ca++ signalling, ion transporter activity, and exocytosis.
Related Pathway Leukocyte transendothelial migrationLong-term potentiation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of EPAC1 in rat skeletal muscle tissue lysate with EPAC1 antibody at 1 ug/mL.
spacer
Immunohistochemistry of EPAC1 in rat brain tissue with EPAC1 antibody at 2.5 ug/mL.
spacer
Immunofluorescence of EPAC1 in rat brain tissue with EPAC1 antibody at 20 ug/mL.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.

Acknowledge