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Anti-TRIM28 Antibody Polyclonal
Also for TRIM28 (NM_005762)
|Rabbit polyclonal TRIM28 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TRIM28.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|TRIM28 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TRIM28 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens tripartite motif containing 28 (TRIM28)|
|KAP1; PPP1R157; RNF96; TF1B; TIF1B|
|TRIM28 Antibody: TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation. |
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Western blot analysis of TRIM28 in human testis tissue lysate with TRIM28 antibody at 1 ug/mL.