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Anti-BCL2L11 Antibody 1C2C8
Also for BCL2L11 (NM_001204106)
|Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.|
||WB: 1 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
|Bim Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.|
|Bim Monoclonal Antibody is immunoaffinity chromotography purified IgG.
|Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 11|
|BAM; BIM; BOD|
|Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.|
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Western blot analysis of (A) 5 and (B) 25 ng of Bim recombinant protein with Bim antibody at 1 ug/mL.
Immunofluorescence of Bim in K562 cells with Bim antibody at 20 ug/mL.