Home Antibody All anti-ZBTB5 antibodies
Anti-ZBTB5 Antibody Polyclonal
Also for ZBTB5 (NM_014872)
|ZBTB5 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ZBTB6.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|ZBTB5 Antibody is supplied in PBS containing 0.02% sodium azide.|
|ZBTB5 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens zinc finger and BTB domain containing 5 (ZBTB5)|
|OTTHUMP00000021384; OTTHUMP00000046108; zinc finger and BTB domain containing 5|
|ZBTB5 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.|
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Western blot analysis of ZBTB5 in mouse brain tissue lysate with ZBTB5 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of ZBTB5 in human brain tissue with ZBTB5 antibody at 2.5 ug/mL.