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Home Antibody All anti-N4BP1 antibodies

Anti-N4BP1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319783 Rabbit Polyclonal N4BP1 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenN4BP1 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human N4BP1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
BufferN4BP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification N4BP1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NEDD4 binding protein 1 (N4BP1)
Alternative NameFLJ31821; KIAA0615; MGC176730
Database LinkNP_694574
Entrez Gene 9683 Human
Entrez Gene 80750 Mouse
Entrez Gene 291921 Rat
FunctionN4BP1 Antibody: Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of N4BP1 in HeLa cell lysate with N4BP1 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.

IF Image
Immunofluorescence of N4BP1 in HeLa cells with N4BP1 antibody at 20 ug/mL.

IF Image
Immunocytochemistry of N4BP1 in HeLa cells with N4BP1 antibody at 10 ug/mL.


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