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Home Antibody All anti-TMEM59 antibodies

Anti-TMEM59 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319781 Rabbit Polyclonal TMEM59 Antibody 100ug $325 In Stock
LC417690 TMEM59 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for TMEM59 (NM_004872)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenTMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferTMEM59 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TMEM59 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens transmembrane protein 59 (TMEM59), transcript variant 2
Alternative NameC1orf8; DCF1; HSPC001; PRO195; UNQ169
Database LinkNP_004863
Entrez Gene 9528 Human
FunctionTMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TMEM59 in human kidney tissue lysate with TMEM59 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

IHC Image
Immunohistochemistry of TMEM59 in human kidney tissue with TMEM59 antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of TMEM59 in human kidney tissue with TMEM59 antibody at 20 ug/mL.


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