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Home Antibody All anti-KL antibodies

Anti-KL Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319778 Rabbit Polyclonal KLOTHO Antibody 100ug $325 In Stock
LC417748 KL HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenKLOTHO antibody was raised against a 16 amino acid synthetic peptide near the center of human KLOTHO.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferKLOTHO Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KLOTHO Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nameklotho
Alternative Name-
Database LinkNP_004786
Entrez Gene 9365 Human
Entrez Gene 16591 Mouse
Entrez Gene 83504 Rat
FunctionKLOTHO Antibody: KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
Related PathwaySecreted ProteinTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KLOTHO in rat heart tissue lysate with KLOTHO antibody at (A) 1 and (B) 2 ug/mL.

IHC Image
Immunohistochemistry of KLOTHO in mouse heart tissue with KLOTHO antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of KLOTHO in mouse heart tissue with KLOTHO antibody at 20 ug/mL.


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