Home Antibody All anti-ULK1 antibodies
Anti-ULK1 Antibody Polyclonal
Also for ULK1 (NM_003565)
|ULK1 antibody was raised against a 16 amino acid peptide near the center of human ULK1 .|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml
|Predicted: 116 kDa Observed: 105 kDa
|ULK1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|ULK1 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens unc-51 like autophagy activating kinase 1 (ULK1)|
|ATG1; ATG1A; hATG1; UNC51; Unc51.1|
Entrez Gene 8408 Human
Entrez Gene 22241 Mouse
Entrez Gene 360827 Rat
|ULK1 Antibody: ULK1, also known as ATG1, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK1 results in a severe defect in the autophagy pathway. ULK1 is highly conserved among eukaryotes, and are the Unc-51-like kinases, ULK1 and ULK2 in mammals. ULK1 is ubiquitously expressed and involved in autophagy in response to starvation. It is the target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13. ULK1 also plays a role early in neuronal differentiation.|
|Protein KinaseDruggable Genome Regulation of autophagymTOR signaling pathway|
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Western blot analysis of ULK1 in rat brain tissue lysate with ULK1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.