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Home Antibody All anti-ULK1 antibodies

Anti-ULK1 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319746 Rabbit Polyclonal ULK1 Antibody 100ug $325 3-7 Days
LC418585 ULK1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenULK1 antibody was raised against a 16 amino acid peptide near the center of human ULK1 .
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 ug/ml
Predicted MW Explanation Predicted: 116 kDa Observed: 105 kDa
BufferULK1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ULK1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens unc-51 like autophagy activating kinase 1 (ULK1)
Alternative NameATG1; ATG1A; hATG1; UNC51; Unc51.1
Database LinkNP_003556
Entrez Gene 8408 Human
Entrez Gene 22241 Mouse
Entrez Gene 360827 Rat
FunctionULK1 Antibody: ULK1, also known as ATG1, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK1 results in a severe defect in the autophagy pathway. ULK1 is highly conserved among eukaryotes, and are the Unc-51-like kinases, ULK1 and ULK2 in mammals. ULK1 is ubiquitously expressed and involved in autophagy in response to starvation. It is the target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13. ULK1 also plays a role early in neuronal differentiation.
Related PathwayProtein KinaseDruggable Genome Regulation of autophagymTOR signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ULK1 in rat brain tissue lysate with ULK1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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