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Home Antibody All anti-TNFSF4 antibodies

Anti-TNFSF4 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319731 Rabbit Polyclonal TNFSF4 Antibody 100ug $325 3-7 Days
LC401143 TNFSF4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for TNFSF4 (NM_003326)
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OriGene Data

ImmunogenRabbit polyclonal TNFSF4 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TNFSF4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 - 1 ug/mL
Predicted MW Explanation 20 kDa
BufferTNFSF4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TNFSF4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4), transcript variant 1
Alternative NameCD134L; CD252; GP34; OX-40L; OX4OL; TXGP1
Database LinkNP_003317
Entrez Gene 7292 Human
Entrez Gene 22164 Mouse
Entrez Gene 89814 Rat
FunctionTNFSF4 Antibody: The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNγ. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TNFSF4 in rat spleen tissue lysate with TNFSF4 antibody at (A) 0.5 and (B) 1 ug/mL

IHC Image
Immunohistochemistry of TNFSF4 in spleen tissue with TNFSF4 antibody at 5 ug/mL.

IF Image
Immunofluorescence of TNFSF4 in human spleen tissue with TNFSF4 antibody at 20 ug/mL.


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