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Anti-TPT1 Antibody Polyclonal
Also for TPT1 (NM_003295)
|Rabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 1 ug/ml, IHC, IF
|TPT1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TPT1 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens tumor protein, translationally-controlled 1 (TPT1), transcript variant 2|
|HRF; p02; p23; TCTP|
Entrez Gene 7178 Human
Entrez Gene 22070 Mouse
Entrez Gene 116646 Rat
|TPT1 Antibody: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer’s disease and Down syndrome. |
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Western blot analysis of TPT1 in human brain tissue lysate with TPT1 antibody at (A) 0.5 and (B) 1 ug/mL.