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Home Antibody All anti-NKX2-1 antibodies

Anti-NKX2-1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319719 Rabbit Polyclonal NKX2-1 Antibody 100ug $325 3-7 Days
LC401141 NKX2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenNKX2-1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NKX2-1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferNKX2-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NKX2-1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NK2 homeobox 1 (NKX2-1), transcript variant 1
Alternative NameBCH; BHC; NK-2; NKX2.1; NKX2A; TEBP; TITF1; TTF-1; TTF1
Database LinkNP_001073136
Entrez Gene 7080 Human
Entrez Gene 21869 Mouse
Entrez Gene 25628 Rat
FunctionNKX2-1 Antibody: NKX2-1 (NK2 homeobox 1) has been identified as a thyroid-specific transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype and morphogenesis. It contains one homeobox DNA-binding domain. NKX2-1 also may play a role in lung development and surfactant homeostasis. Mutations and deletions in this gene are associated with benign hereditary chorea, congenital hypothyroidism, neonatal respiratory distress, and may be associated with thyroid cancer. NKX2-1 has been suggested to be a candidate suppressor of malignant progression.
Related PathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NKX2-1 in rat lung tissue lysate with NKX2-1 antibody at (A) 1 and (B) 2 ug/mL.

IHC Image
Immunohistochemistry of NKX2-1 in human lung tissue with NKX2-1 antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of NKX2-1 in human lung tissue with NKX2-1 antibody at 20 ug/mL.


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