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Home Antibody All anti-STAT3 antibodies

Anti-STAT3 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319710 Rabbit Polyclonal STAT3 Antibody 100ug $325 3-7 Days
LC403728 STAT3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRabbit polyclonal STAT3 antibody was raised against a 19amino acid peptide near the amino terminus of human STAT3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC, IF
Predicted MW Explanation 85 kDa
BufferSTAT3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification STAT3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 2
Alternative NameADMIO; APRF; HIES
Database LinkNP_003141
Entrez Gene 6774 Human
Entrez Gene 20848 Mouse
Entrez Gene 25125 Rat
FunctionSTAT3 Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT3 signals are pivotal to the proliferation and differentiation of neural stem cells and also participate in neuronal regeneration and cancers of the nervous system.
Related PathwayTranscription FactorsDruggable Genome Chemokine signaling pathwayJak-STAT signaling pathwayAdipocytokine signaling pathwayPathways in cancerPancreatic cancerAcute myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of STAT3 in human small intestine tissue lysate with STAT3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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