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Anti-STAT3 Antibody Polyclonal
Also for STAT3 (NM_003150)
|Rabbit polyclonal STAT3 antibody was raised against a 19amino acid peptide near the amino terminus of human STAT3.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, IHC, IF
|STAT3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|STAT3 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 2|
|ADMIO; APRF; HIES|
Entrez Gene 6774 Human
Entrez Gene 20848 Mouse
Entrez Gene 25125 Rat
|STAT3 Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT3 signals are pivotal to the proliferation and differentiation of neural stem cells and also participate in neuronal regeneration and cancers of the nervous system. |
|Transcription FactorsDruggable Genome Chemokine signaling pathwayJak-STAT signaling pathwayAdipocytokine signaling pathwayPathways in cancerPancreatic cancerAcute myeloid leukemiaMore Pathways >> |
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Western blot analysis of STAT3 in human small intestine tissue lysate with STAT3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.