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Anti-CCL2 Antibody Polyclonal
Also for CCL2 (NM_002982)
|Rabbit polyclonal CCL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human CCL2.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||ELISA, WB: 1 - 2 ug/ml, IHC, IF
|CCL2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|CCL2 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens chemokine (C-C motif) ligand 2 (CCL2)|
|GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF|
|CCL2 Antibody: CCL2, also known as monocyte chemotactic protein 1 (MCP1), belongs to the intercrine beta (chemokine CC) family. It is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. It is upregulated during infection and inflammation. CCL2 is a potent basophil activator but does not affect eosinophils, whereas the related protein MCP2 stimulates both eosinophils and basophils. MCP3 has been shown to have the broadest range of influence. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. |
Cytokine-cytokine receptor interaction
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Western blot analysis of CCL2 in rat spleen tissue lysate with CCL2 antibody at 1 ug/mL.