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Home Antibody All anti-ROCK1 antibodies

Anti-ROCK1 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319700
  • Rabbit Polyclonal ROCK1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417325) , 20ug Explanation
100ug $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenROCK1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ROCK1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferROCK1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ROCK1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens Rho-associated, coiled-coil containing protein kinase 1 (ROCK1)
Alternative NameP160ROCK; ROCK-I
Database LinkNP_005397
Entrez Gene 6093 Human
Entrez Gene 19877 Mouse
Entrez Gene 81762 Rat
FunctionROCK1 Antibody: ROCK1 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK1 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK1, like its isozyme ROCK2, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.
Related PathwayProtein KinaseDruggable Genome Chemokine signaling pathwayVascular smooth muscle contractionWnt signaling pathwayTGF-beta signaling pathwayAxon guidanceFocal adhesionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ROCK1 in 293 cell lysate with ROCK1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of ROCK1 in 293 cells with ROCK1 antibody at 20 ug/mL.
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