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Anti-ROCK1 Antibody Polyclonal
Also for ROCK1 (NM_005406)
|ROCK1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ROCK1.|
|Human, Mouse, Rat
||WB: 1 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
|ROCK1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|ROCK1 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens Rho-associated, coiled-coil containing protein kinase 1 (ROCK1)|
|ROCK1 Antibody: ROCK1 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK1 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK1, like its isozyme ROCK2, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis. |
Signaling by GPCR
TGF Beta Signaling Pathway
Wnt Signaling Pathway
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Western blot analysis of ROCK1 in 293 cell lysate with ROCK1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of ROCK1 in 293 cells with ROCK1 antibody at 20 ug/mL.