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Anti-RBBP8 Antibody Polyclonal
Also for RBBP8 (NM_002894)
|RBBP8 antibody was raised against a 14 amino acid synthetic peptide near the center of human RBBP8.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|RBBP8 Antibody is supplied in PBS containing 0.02% sodium azide.|
|RBBP8 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens retinoblastoma binding protein 8 (RBBP8), transcript variant 1|
|COM1; CTIP; JWDS; RIM; SAE2; SCKL2|
|RBBP8 Antibody: RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.|
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Western blot analysis of RBBP8 in mouse spleen tissue lysate with RBBP8 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of RBBP8 in rat spllen tissue with RBBP8 antibody at 5 ug/mL.