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Home Antibody All anti-NCBP1 antibodies

Anti-NCBP1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319688
  • Rabbit Polyclonal NCBP1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419301) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for NCBP1 (NM_002486)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenNCBP1 antibody was raised against a 17 amino acid peptide near the center of human NCBP1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml
BufferNCBP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NCBP1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens nuclear cap binding protein subunit 1, 80kDa (NCBP1)
Alternative NameCBP80; NCBP; Sto1
Database LinkNP_002477
FunctionNCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay (1,2). Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation (3).
Related Pathway

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WB Image
Western blot analysis of NCBP1 in HeLa cell lysate with NCBP1 antibody at (A) 1 and (B) 2 ug/mL.

 

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