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Anti-NCBP1 Antibody Polyclonal
Also for NCBP1 (NM_002486)
|NCBP1 antibody was raised against a 17 amino acid peptide near the center of human NCBP1.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|NCBP1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|NCBP1 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens nuclear cap binding protein subunit 1, 80kDa (NCBP1)|
|CBP80; NCBP; Sto1|
|NCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay (1,2). Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation (3).|
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Western blot analysis of NCBP1 in HeLa cell lysate with NCBP1 antibody at (A) 1 and (B) 2 ug/mL.