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Home Antibody All anti-FOXO4 antibodies

Anti-FOXO4 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319684 Rabbit Polyclonal FOXO4 Antibody 100ug $325 3-7 Days
LC401798 FOXO4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenFOXO4 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human FOXO4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5 - 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
BufferFOXO4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification FOXO4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nameforkhead box O4
Alternative NameAFX|AFX1|MLLT7
Database LinkNP_001164402
Entrez Gene 4303 Human
Entrez Gene 54601 Mouse
Entrez Gene 302415 Rat
FunctionFOXO4 Antibody: FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In the absence of PI3K/AKT activation, FOXO4 localizes in the nucleus where it functions as a transcription factor. FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS), resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS. It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity.
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FOXO4 in A-20 cell lysate with FOXO4 antibody at (A) 0.5 and (B) 1 ug/mL.

IF Image
Immunocytochemistry of FOXO4 in HeLa cells with FOXO4 antibody at 10 ug/mL.


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