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Anti-LY9 Antibody Polyclonal
|SLAMF3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SLAMF3.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
|SLAMF3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|SLAMF3 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens lymphocyte antigen 9 (LY9), transcript variant 1|
|CD229; hly9; mLY9; SLAMF3|
|SLAMF3 Antibody: The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family. SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP. Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2). Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.|
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Western blot analysis of SLAMF3 in 293 cell lysate with SLAMF3 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry of SLAMF3 in 293 cells with SLAMF3 antibody at 10 ug/mL.