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Home Antibody All anti-LY9 antibodies

Anti-LY9 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319679
  • Rabbit Polyclonal SLAMF3 Antibody
100ug $325 3-7 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)

OriGene Data

ImmunogenSLAMF3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SLAMF3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferSLAMF3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification SLAMF3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens lymphocyte antigen 9 (LY9), transcript variant 1
Alternative NameCD229; hly9; mLY9; SLAMF3
Database LinkNP_002339
Entrez Gene 4063 Human
Entrez Gene 17085 Mouse
Entrez Gene 289227 Rat
FunctionSLAMF3 Antibody: The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family. SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP. Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2). Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of SLAMF3 in 293 cell lysate with SLAMF3 antibody at (A) 1 and (B) 2 ug/mL.
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Immunofluorescence of SLAMF3 in 293 cells with SLAMF3 antibody at 20 ug/mL.
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