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Home Antibody All anti-KPNA2 antibodies

Anti-KPNA2 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319672
  • Rabbit Polyclonal KPNA2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419418) , 20ug Explanation
100ug 325 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for KPNA2 (NM_002266)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenKPNA2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferKPNA2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KPNA2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2)
Alternative NameIPOA1; QIP2; RCH1; SRP1alpha
Database LinkNP_002257
Entrez Gene 3838 Human
Entrez Gene 16647 Mouse
Entrez Gene 85245 Rat
FunctionKPNA2 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA2 is the alpha subunit 2 of karyopherin, which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. It is ubiquitously expressed and contains an IBB/importin beta domain, ten Armadillo repeats that bind "cargo" and three intervening nuclear localization sequences (NLSs). It has recently been reported to play an important role in tumorigenesis and tumor progression.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KPNA2 in rat heart tissue lysate with KPNA2 antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of KPNA2 in human heart tissue with KPNA2 antibody at 5 ug/mL.
IF Image
Immunofluorescence of KPNA2 in human heart tissue with KPNA2 antibody at 20 ug/mL.

 

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