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Home Antibody All anti-IL15 antibodies

Anti-IL15 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319665 Rabbit Polyclonal IL-15 Antibody 100ug $325 3-7 Days
LC403532 IL15 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation 18 kDa
BufferIL-15 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IL-15 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nameinterleukin 15
Alternative NameIL-15
Database LinkNP_000576
Entrez Gene 3600 Human
Entrez Gene 16168 Mouse
Entrez Gene 25670 Rat
FunctionIL-15 Antibody: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IL-15 in rat spleen tissue lysate with IL-15 antibody at (A) 1 and (B) 2 ug/mL

IHC Image
Immunohistochemistry of IL-15 in spleen tissue with IL-15 antibody at 2.5 ug/mL.


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