OriGene Logo
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
Home Antibody All anti-IDH2 antibodies

Anti-IDH2 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319664 Rabbit Polyclonal IDH2 Antibody 100ug $325 2 Weeks
LC400787 IDH2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
Add to Shopping Cart

OriGene Data

ImmunogenIDH2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human IDH2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferIDH2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IDH2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nameisocitrate dehydrogenase (NADP(+)) 2, mitochondrial
Database LinkNP_002159
Entrez Gene 3418 Human
Entrez Gene 269951 Mouse
Entrez Gene 361596 Rat
FunctionIDH2 Antibody: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. Both IDH1 and IDH2 play significant roles in the tricarboxylic acid cycle (TCA), and defects in IDH1 as well as IDH2 have been implicated in the development of glioma as well as other malignancies.
Related Pathway Citrate cycle (TCA cycle)Glutathione metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IDH2 in human heart tissue lysate with IDH2 antibody at (A) 1 and (B) 2 ug/mL.

IHC Image
Immunohistochemistry of IDH2 in mouse heart tissue with IDH2 antibody at 5 ug/mL.

IF Image
Immunofluorescence of IDH2 in mouse heart tissue with IDH2 antibody at 20 ug/mL.


Inc 5000 Healthcare Company

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.