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Home Antibody All anti-FOXO3 antibodies

Anti-FOXO3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319652
  • Rabbit Polyclonal FOXO3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400566) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for FOXO3 (NM_001455)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFOXO3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human FOXO3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, ICC: 4 ug/ml, IF: 20 ug/ml
BufferFOXO3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification FOXO3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens forkhead box O3 (FOXO3), transcript variant 1
Alternative NameAF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A
Database LinkNP_001446
FunctionFOXO3 Antibody: FOXO3 is a ubiquitously expressed 75 kDa protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. FOXO3 is involved with mTOR in the regulation of autophagy in skeletal muscle, and activates protein degradation in atrophying muscle cells. FOXO3 has also been implicated in several neurodegenerative disorders including aging, neuromuscular disease, systemic lupus erythmatosus, stroke and diabetic complications.
Related Pathway
TGF Beta Signaling Pathway

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WB Image
Western blot analysis of FOXO3 in A-20 cell lysate with FOXO3 antibody at (A) 0.5 and (B) 1 ug/mL.
IF Image
Immunocytochemistry of FOXO3 in A-20 cells with FOXO3 antibody at 4 ug/mL.

 

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