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Anti-DYRK1A Antibody Polyclonal
Also for DYRK1A (NM_001396)
|DYRK1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human DYRK1A.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, ICC: 10 ug/ml
|DYRK1A Antibody is supplied in PBS containing 0.02% sodium azide.|
|DYRK1A Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 1|
|DYRK; DYRK1; HP86; MNB; MNBH; MRD7|
|DYRK1A Antibody: DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family and is thought to be involved in neuronal differentiation, neurodegenerative diseases, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. DYRK1A phosphorylates several transcription factors such as p53, leading to inhibition of embryonic neuronal cell proliferation. DYRK1A associates with multiple proteins, including SPRED1 and SPRED2; this association appears to inhibit the phosphorylation activity of DYRK1A. Recent evidence also suggests that DYRK1A may be involved in the replication of HIV-1.|
Hedgehog signaling pathway
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Western blot analysis of DYRK1A in HeLa cell lysate with DYRK1A antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry of DYRK1A in HeLa cells with DYRK1A antibody at 10 ug/mL.