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Home Antibody All anti-DYRK1A antibodies

Anti-DYRK1A Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319637
  • Rabbit Polyclonal DYRK1A Antibody
100ug $325 3-7 Days
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WB(1)
IF(1)
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Also for DYRK1A (NM_001396)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenDYRK1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human DYRK1A.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 10 ug/ml
BufferDYRK1A Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DYRK1A Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 1
Alternative NameDYRK; DYRK1; HP86; MNB; MNBH; MRD7
Database LinkNP_001387
FunctionDYRK1A Antibody: DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family and is thought to be involved in neuronal differentiation, neurodegenerative diseases, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. DYRK1A phosphorylates several transcription factors such as p53, leading to inhibition of embryonic neuronal cell proliferation. DYRK1A associates with multiple proteins, including SPRED1 and SPRED2; this association appears to inhibit the phosphorylation activity of DYRK1A. Recent evidence also suggests that DYRK1A may be involved in the replication of HIV-1.
Related Pathway
Hedgehog signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DYRK1A in HeLa cell lysate with DYRK1A antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of DYRK1A in HeLa cells with DYRK1A antibody at 10 ug/mL.

 

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