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Anti-DAP Antibody Polyclonal
|DAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|DAP Antibody is supplied in PBS containing 0.02% sodium azide.|
|DAP Antibody is affinity chromatography purified via peptide column.
|Homo sapiens death-associated protein (DAP)|
|DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).|
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Western blot analysis of DAP in human small intestine tissue lysate with DAP antibody at 1 ug/mL.