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Home Antibody All anti-BCL6 antibodies

Anti-BCL6 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319620 Rabbit Polyclonal BCL6 Antibody 100ug $325 3-7 Days
LC400639 BCL6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenBCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 ug/ml
Predicted MW Explanation 78 kDa
BufferBCL6 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification BCL6 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 2
Alternative NameBCL5; BCL6A; LAZ3; ZBTB27; ZNF51
Database LinkNP_001124317
Entrez Gene 604 Human
Entrez Gene 12053 Mouse
Entrez Gene 303836 Rat
FunctionBCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of BCL6 in rat lung tissue lysate with Bcl6 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide
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