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Anti-Esrp1 Antibody 27H12


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SKU Description Amount Price Availability*  
TA319607 Mouse monoclonal Esrp-1 antibody 100ug $356 3-7 Days
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OriGene Data

ImmunogenAnti-Esrp-1 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein.
Clone Name27H12 Isotype
Species ReactivityMouse Concentration1.0 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:750,000, WB: 1:1000
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note Epithelial splicing regulatory protein 1 (Esrp-1) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). EsrpP-1 acts by directly binding specific sequences in mRNAs. It binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Reference Data

Target NameMus musculus epithelial splicing regulatory protein 1 (Esrp1), transcript variant 1
Alternative Name2210008M09Rik; A630065D16; BC031468; Rbm35a
Database LinkNP_918944
Entrez Gene 207920 Mouse
Related Pathway

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WB Image
Anti-ESRP-1 by WB shows detection of ESRP-1 in transfected 293T cell extracts (lane 2, arrowhead). Lanes 1 and 3 contain GFP-transfected- and ESRP2-transfected 293T cell lysates, respectively. Briefly, each lane contains approximately 5 µg of lysate. Primary antibody was used at a 1:1000 dilution and followed reacted with a 1:10,000 dilution of an anti-mouse ECL antibody for 1hr at room temperature.


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