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Home Antibody All anti-BIN3 antibodies

Anti-BIN3 Antibody 3A4

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319552
  • Mouse monoclonal anti-BIN3 antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402705) , 20ug Explanation
100ug 325 3-7 Days
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WB(2)
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Also for BIN3 (NM_018688)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenAnti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a full legnth human BIN3 recombinant protein followed by hybridoma development.
Clone Name3A4 Isotype
Species Reactivitymouse, human Concentration1.0 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:5000-1:50000, WB: 1:500-1:1500, IP: 10-100 uL
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non–Hodgkin’s lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.

Reference Data

Target NameHomo sapiens bridging integrator 3 (BIN3)
Alternative NameMGC14978
Database LinkNP_061158
Entrez Gene 55909 Human
Entrez Gene 57784 Mouse
Function
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western Blot of Mouse Anti-BIN3 antibody. Lane 1: MEF cells wild type. Lane 2: MEF cells null mice. Load: 35 µg per lane. Primary antibody: BIN3 antibody overnight at 4°C. Secondary antibody: IRDye800™ mouse secondary antibody for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 29.7 kDa, 30 kDa for BIN-3. Other band(s): non-specific.
WB Image
Western Blot of Mouse anti-BIN3 antibody. Lane 1: MEF lysate BIN3 +/-. Lane 2: MEF lysate BIN3 -/-. Load: 35 µg per lane. Primary antibody: BIN-3 antibody at 1:400 for overnight at 4°C. Secondary antibody: IRDye800™ mouse secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 29.7 kDa, 31 kDa for BIN 3. Other band(s): * non-specifics.

 

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