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Anti-STAT1 PHOSPHO Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319404 Rabbit polyclonal STAT1 phospho Y701 antibody (Phospho-specific) 100ug $356 3-7 Days
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OriGene Data

ImmunogenThis Protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Y701 in the mouse STAT1 protein.
Clone Name IsotypeIgG
Species Reactivitymouse, rat Concentration2.3 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:25,000, WB: 1:500 - 1:2,000
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Signal transducer and activator of transcription 1 (Stat1) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor.  Phosphorylation of Stat1 at Tyr701 induces Stat1 dimerization, nuclear translocation and DNA binding. Stat1 has two isoforms,

Reference Data

Target NameMus musculus signal transducer and activator of transcription 1 (Stat1), transcript variant 2
Alternative Name2010005J02Rik; AA408197
Database LinkNP_033309
Entrez Gene 20846 Mouse
Entrez Gene 25124 Rat
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot using Protein A purified anti-Stat1 pY701 antibody shows detection of phosphorylated Stat1 (indicated by arrowhead at ~91 kDa) in K562 cells after 30 min treatment with 1Ku of hIFN-??(lane 2). No reactivity is seen for non-phosphorylated Stat1 in untreated cells (lane 1). The membrane was probed with the primary antibody at a 1:1,000 dilution at 4° C, overnight. Personal Communication from Ana Gamero, CCR-NCI, Bethesda, MD.


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