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Home Antibody All anti-BACH1 antibodies

Anti-BACH1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319228 Rabbit polyclonal anti-BACH1 antibody 100ug $325 3-7 Days
LC410352 BRIP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 92-104 of isoform 1 of human BACH1 protein.
Clone Name IsotypeIgG
Species Reactivityhuman Concentration1.0 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:10,000 - 1:44,000, WB: 1:500- 1:2,000
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note BACH1 (also known as BRCA1 interacting protein C-terminal helicase 1, BRCA1-interacting protein 1 and BRCA1-associated C-terminal helicase 1) is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). The BACH1 gene may be a target of germline cancer-inducing mutations.   BACH1 is localized within the nucleus and functions as a DNA-dependent ATPase and 5' to 3' DNA helicase.  Two isoforms have been identified for this protein.

Reference Data

Target NameHomo sapiens BRCA1 interacting protein C-terminal helicase 1 (BRIP1)
Alternative NameBACH1; FANCJ; OF
Database LinkNP_114432
Entrez Gene 83990 Human
Function
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB using Anti-BACH1 antibody shows detection of a band at ~105 kDa (lane 1) corresponding to human BACH1 present in a 293 whole cell lysate (arrowhead). Lane 2 shows that specific band staining is competed out when the antibody is pre-incubated with the peptide immunogen prior to reaction. The primary antibody was diluted to 1:1,000. IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX was used at 1:10000.
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