Home Antibody All anti-MIF antibodies
|Synthetic peptide surrounding amino acid 67 of human MIF|
||WB: 0.5-4 ug/ml, IP: 5-10ug/ml
|100 µg (0.2 mg/ml) affinity purified rabbit anti-MIF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Homo sapiens macrophage migration inhibitory factor (glycosylation-inhibiting factor) (MIF)|
|GIF; GLIF; MMIF|
Entrez Gene 17319 Mouse
Entrez Gene 81683 Rat
|MIF (macrophage migration inhibitory factor) was one of the first cytokine activities to be discovered and was initially described as a T cell-derived factor that inhibits the random migration of microphages. Recently, MIF was rediscovered as a pituitary hormone that acts as the counter-regulatory hormone for glucocorticoid action within the immune system. MIF was released from macrophages and T-cells in response to physiological concentrations of glucocorticoids. The secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production. MIF also plays a critical role in the host control of inflammation and immunity. |
|Druggable Genome Tyrosine metabolismPhenylalanine metabolism|
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Western blot analysis of MIF expression in lysates from Jurkat (Lane 1, 2), 3T3 (Lane 3) and rat kidney (Lane 4).