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Home Antibody All anti-LMX1A antibodies

Anti-LMX1A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319062
  • Rabbit polyclonal anti-LMX1A antibody (CT)
100ug 345 3-7 Days
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WB(1)

OriGene Data

ImmunogenRabbit polyclonal LMX1A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LMX1A.
Clone Name IsotypeRabbit IgG1
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-2 ug/ml, ELISA
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens LIM homeobox transcription factor 1, alpha (LMX1A), transcript variant 2
Alternative NameLMX-1; LMX1; LMX1.1; MGC87616;sst; Lmx1.1; MGC129356; MGC129357; dr; dreher; OTTMUSP00000022889; OTTMUSP00000022890; shaker short-tail; LIM homeobox transcription factor 1 alpha
Database LinkNP_796373
FunctionThe LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
Related Pathway

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WB Image
Western blot analysis of LMX1A in rat brain tissue lysate with LMX1A antibody at (A) 1 and (B) 2 µg/mL.

 

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