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Home Antibody All anti-Ccl2 antibodies

Anti-Ccl2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319048
  • Rabbit polyclonal anti-CCL2 (MCP-1) antibody
100ug 325 3-7 Days
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WB(1)
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Also for Ccl2 (NM_002982)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenE. coli-expressed rat MCP-1 (a.a. 1-73)
Clone Name IsotypeRabbit IgG
Species ReactivityMouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-2 ug/ml
Buffer100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-rat MCP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Purification Affinity purified

Reference Data

Target NameHomo sapiens chemokine (C-C motif) ligand 2 (CCL2)
Alternative NameGDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF
Database LinkNP_002973
FunctionRat MCP-1/JE (monocyte chemoattractant protein-1) is a 148-amino acid CC chemokine with a N-terminal sequence of 29 residues as a signal sequence. It was originally cloned from Con-A-stimulated rat spleen cDNA library. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3’-end. The 3’-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation and which explains for the higher molecular weight (25 kDa). In vitro, MCP-1/JE is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophiles. MCP-1/JE is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli.
Related Pathway
Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MCP-1 in LPS treated RAW cell lysate.

 

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