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Anti-Ccl2 Antibody


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SKU Description Amount Price Availability*  
TA319048 Rabbit polyclonal anti-CCL2 (MCP-1) antibody 100ug $482 3-7 Days
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OriGene Data

ImmunogenE. coli-expressed rat MCP-1 (a.a. 1-73)
Clone Name IsotypeRabbit IgG
Species ReactivityMouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-2 ug/ml
Buffer100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-rat MCP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Purification Affinity purified

Reference Data

Target NameC-C motif chemokine ligand 2
Alternative NameGDCF-2|HC11|HSMCR30|MCAF|MCP-1|MCP1|SCYA2|SMC-CF
Database LinkNP_002973
Entrez Gene 20296 Mouse
Entrez Gene 24770 Rat
FunctionRat MCP-1/JE (monocyte chemoattractant protein-1) is a 148-amino acid CC chemokine with a N-terminal sequence of 29 residues as a signal sequence. It was originally cloned from Con-A-stimulated rat spleen cDNA library. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3’-end. The 3’-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation and which explains for the higher molecular weight (25 kDa). In vitro, MCP-1/JE is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophiles. MCP-1/JE is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli.
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayNOD-like receptor signaling pathway

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WB Image
Western blot analysis of MCP-1 in LPS treated RAW cell lysate.


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