Home Antibody All anti-CX3CL1 antibodies
Also for CX3CL1 (NM_002996)
|E. coli-expressed recombinant human Fractalkine|
|Human, mouse, rat
||WB: 0.5-4 ug/ml, IHC: 10-20ug/ml, IP: 4-8ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens chemokine (C-X3-C motif) ligand 1 (CX3CL1), transcript variant 1|
|ABCD-3; C3Xkine; CXC3; CXC3C; fractalkine; neurotactin; NTN; NTT; SCYD1|
Entrez Gene 6376 Human
Entrez Gene 20312 Mouse
Entrez Gene 89808 Rat
|Fractalkine, also known as neurotactin, is a membrane-bound CX3C Chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain, the first two cysteine residues are separated by 3 amino acids (CX3C). Fractalkine message is found in high abundance in the brain, kidney, lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells and may play a role in brain inflammation. |
|Secreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathway|
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Western blot analysis using recombinant human Fractalkine. Lane 1: 1 µg, Lane 2: 250 ng.