Home Antibody All anti-CX3CL1 antibodies
Also for CX3CL1 (NM_002996)
|E. coli-expressed recombinant human Fractalkine|
|Human, mouse, rat
||WB: 0.5-4 ug/ml, IHC: 10-20ug/ml, IP: 4-8ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Affinity purified (Protein A or G Sepharose)
|Homo sapiens chemokine (C-X3-C motif) ligand 1 (CX3CL1)|
|ABCD-3; C3Xkine; CXC3; CXC3C; fractalkine; neurotactin; NTN; NTT; SCYD1|
|Fractalkine, also known as neurotactin, is a membrane-bound CX3C Chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain, the first two cysteine residues are separated by 3 amino acids (CX3C). Fractalkine message is found in high abundance in the brain, kidney, lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells and may play a role in brain inflammation. |
Cytokine-cytokine receptor interaction
Signaling by GPCR
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Western blot analysis using recombinant human Fractalkine. Lane 1: 1 µg, Lane 2: 250 ng.