Home Antibody All anti-Pik3ca antibodies
Also for Pik3ca (NM_006218)
|Synthetic peptide surrounding amino acid 505 of mouse P13 kinase. |
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA)|
|CLOVE; CWS5; MCAP; MCM; MCMTC; p110-alpha; PI3K|
Entrez Gene 5290 Human
Entrez Gene 18706 Mouse
Entrez Gene 170911 Rat
|Phosphatidylinositol 3-kinase (PI 3-kinase), is a phosphoinositide-specific protein kinase that plays a central role in mitogenic signal transduction leading to cellular regulation, cell growth and differentiation, and oncogenesis. PI 3-kinase associates with, and is activated by a wide range of tyrosine kinase receptors including EGF, PDGF, CSF-1, erbB-3 and insulin receptor, non-receptor protein-tyrosine kinases of the src family (e.g. pp60src), and crk and abl proto-oncogene products. PI 3-kinase is involved in signal transduction in terminally differentiated, activated cells like platelets and neutrophils.|
|Druggable Genome Inositol phosphate metabolismErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisMore Pathways >> |
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Western blot analysis of PI3-Kinase with lysate from Jurkat cells.