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Home Antibody All anti-Ppargc1a antibodies

Anti-Ppargc1a Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319007 Rabbit polyclonal anti-PGC-1alpha antibody 100ug $325 In Stock
LC402235 PPARGC1A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 766 of mouse PGC-1alpha
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PPARGC1A)
Alternative NameLEM6; PGC-1(alpha); PGC-1v; PGC1; PGC1A; PPARGC1
Database LinkNP_037393
Entrez Gene 10891 Human
Entrez Gene 19017 Mouse
Entrez Gene 83516 Rat
FunctionThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may also be involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Related PathwayTranscription FactorsDruggable Genome Insulin signaling pathwayAdipocytokine signaling pathwayHuntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of PGC-1alpha with Jurkat cell lysate (Lane 1 & 2).
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