Home Antibody All anti-Pim1 antibodies
Also for Pim1 (NM_001243186)
|Synthetic peptide surrounding amino acid 296 of rat PIM1|
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit anti-PIM1 polyclonal antibody in phosphate (PBS, pH 7.2) containing 30% glycerol, 0.5 % BSA and 0.01% thimerosal.|
|Homo sapiens Pim-1 proto-oncogene, serine/threonine kinase (PIM1), transcript variant 1|
Entrez Gene 5292 Human
Entrez Gene 18712 Mouse
Entrez Gene 24649 Rat
|The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Recently, Pim1 has been shown to enhance the activities of p100, c-Myb and Cdc 25a and in part this might explain reported effects of Pim1 on mitogenesis. |
|Protein KinaseES Cell Differentiation/IPSDruggable Genome Jak-STAT signaling pathwayAcute myeloid leukemia|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of PIM1 using Jurkat cell lysate.