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Home Antibody All anti-Pim1 antibodies

Anti-Pim1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318959
  • Rabbit polyclonal anti-PIM1 antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419183) , 20ug
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 296 of rat PIM1
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti-PIM1 polyclonal antibody in phosphate (PBS, pH 7.2) containing 30% glycerol, 0.5 % BSA and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens pim-1 oncogene (PIM1), transcript variant 1
Alternative NamePIM
Database LinkNP_001230115
FunctionThe proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Recently, Pim1 has been shown to enhance the activities of p100, c-Myb and Cdc 25a and in part this might explain reported effects of Pim1 on mitogenesis.
Related Pathway
Jak-STAT signaling pathway

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WB Image
Western blot analysis of PIM1 using Jurkat cell lysate.

 

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