Home Antibody All anti-DVL3 antibodies
Also for DVL3 (NM_004423)
|Synthetic peptide surrounding amino acid 583 of mouse Dvl3|
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens dishevelled segment polarity protein 3 (DVL3)|
Entrez Gene 1857 Human
Entrez Gene 13544 Mouse
Entrez Gene 303811 Rat
|Dvl1, Dvl2, and Dvl3 are mammalian homologs of Dsh (disheveled) proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins, Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers. |
Wnt Signaling Pathway
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Western blot analysis of Dvl3 in Jurkat cell lysate (Lane 1& 2) and 3T3 cell lysate (Lane 3).